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Why do I keep getting skin infections over and over again?

By Sina Hartung, MMSC-BMI, Harvard Medical SchoolReviewed by Eureka Health Medical Group
Published: July 24, 2025Updated: July 24, 2025

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Key Takeaways

Recurrent skin infections often signal an underlying issue: uncontrolled eczema or diabetes, bacterial colonisation with Staphylococcus aureus, weakened immunity, or hygiene factors that allow germs to re-enter broken skin. Tackling both the infection and its root cause—through targeted swabs, blood sugar checks, skin-barrier repair, and sometimes decolonisation therapy—usually stops the cycle.

Could one hidden cause be driving my repeat skin infections?

Most people with back-to-back boils, impetigo, or cellulitis have a single driver—often a chronic skin condition or metabolic issue—that keeps the door open for microbes. Identifying and fixing that driver is the fastest way to break the cycle.

  • Eczema cracks invite bacteriaUp to 80 % of patients with atopic eczema are colonised by Staphylococcus aureus, making flare-ups and infections a package deal.
  • Uncontrolled blood sugar feeds germsPeople with HbA1c above 8 % have roughly double the risk of skin abscesses because high glucose weakens neutrophil function.
  • Hidden immune deficits matterLow IgG subclasses, HIV, or chronic steroid use blunt the body’s first defense and allow minor cuts to become major infections.
  • Nasal staph colonisation is commonAbout one in three healthy adults carry S. aureus in their nostrils; in persistent carriers, odds of skin infections rise six-fold.
  • Quote from Sina Hartung, MMSC-BMI“When patients ask why infections keep returning, I first look for a skin-barrier problem or metabolic trigger before adding more antibiotics.”
  • Nearly half of staph skin infections come backRecurrent Staphylococcus aureus skin and soft-tissue infections develop in roughly 45–50 % of patients after an initial episode, highlighting the importance of finding and fixing predisposing host factors. (NIH)
  • Two or more antibiotic rounds a year signal possible immunodeficiencyAccording to the AAAAI, adults who require antibiotics for infections more than twice in a 12-month period should be evaluated for an underlying primary immune deficiency rather than just receiving repeated short courses of treatment. (AAAAI)
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When should recurring skin infections make me worry about something serious?

Some patterns point to urgent problems such as invasive MRSA or deep immune failure. Seek care fast if any of these appear.

  • Rapidly spreading redness over hoursCellulitis expanding more than 2 cm per hour suggests toxin-producing bacteria and warrants same-day IV antibiotics.
  • Fever above 38.5 °C with rigorsSystemic signs raise suspicion for sepsis; hospital evaluation prevents organ damage.
  • Failure of two oral antibiotic coursesPersistent infection after 10–14 days on appropriate drugs indicates resistant organisms or an abscess needing drainage.
  • Infections at unusual sitesRecurrent perianal or periorbital abscesses can flag Crohn’s disease or sinus-based staph reservoirs.
  • Quote from the team at Eureka Health“We tell patients: if pain outpaces over-the-counter pain relief or redness races past a joint line, call or come in immediately.”
  • More than two antibiotic-treated skin infections per yearThe AAAAI lists ≥2 courses of antibiotics for bacterial infections within a single year in adults as a hallmark of possible primary immune deficiency that should prompt specialist evaluation. (AAAAI)
  • Recurrent boils in diabetics warrant a blood-sugar checkJohnson Memorial Health highlights diabetes as a leading driver of repeat boils and carbuncles; poor glycemic control weakens defenses, so screening for hyperglycemia is recommended when skin abscesses keep returning. (JMH)

What practical steps at home reduce future flare-ups?

Daily habits matter as much as prescriptions. Strengthen the skin barrier, cut bacterial load, and control underlying diseases to slash recurrence rates.

  • Use bleach-in-bath twice weeklyA half-cup of household bleach in a full tub (150 L) for 10 minutes lowers surface staph counts by 90 %.
  • Moisturise within 3 minutes of showeringLocking in water restores the lipid layer and halves eczema fissures that let bacteria in.
  • Switch to fragrance-free detergentsIrritants in scented products can raise skin pH above 5.5, making it friendlier for S. aureus.
  • Keep glucose in target rangeEach 1 % drop in HbA1c correlates with a 21 % fall in skin infection risk among type 2 diabetics.
  • Quote from Sina Hartung, MMSC-BMI“Simple barrier care—emollients, gentle cleansers, short showers—often outperforms another round of antibiotics in the long term.”
  • Quit smoking to dampen chronic inflammationHealthline lists smoking as a major trigger for hidradenitis suppurativa; patients who give up cigarettes often report fewer painful breakouts within months. (Healthline)
  • Rinse with chlorhexidine soap after workoutsTareen Dermatology recommends surgical washes like Hibiclens to lower bacterial counts on sweaty skin folds and reduce the chance of new abscesses forming. (TareenDerm)

Which tests and treatments actually break the infection cycle?

Targeted investigations pick up correctable problems, while evidence-based therapies—not just another random antibiotic—cut relapse.

  • Skin swab with culture and sensitivityIdentifies MRSA vs MSSA; a 2019 study showed tailored antibiotics reduce 3-month recurrence by 35 %.
  • HbA1c and fasting glucoseDetects diabetes in one in five adults who present with recurrent cellulitis.
  • Serum IgG, IgA, IgM panelsLow levels prompt immunology referral; replacement therapy halves infections in CVID.
  • Nasal mupirocin plus chlorhexidine washA 5-day decolonisation regimen cut MRSA skin infections by 56 % in household members.
  • Quote from the team at Eureka Health“We order cultures early—guessing the bug is why many patients bounce back with the same infection.”
  • Controlling diabetes and obesity cuts skin infection relapseA review reports recurrent SSTIs in up to 45 % of patients, with diabetes, obesity and immunosuppression among key modifiable drivers; managing these factors is central to lowering repeat infections. (NIH)
  • Risk-stratified prophylaxis limits resistance while reducing recurrencesEvidence suggests decolonisation and prophylactic antibiotics can curb repeat MRSA infections in selected high-risk groups, but routine use may erode effectiveness and cause adverse effects—highlighting the need for tailored strategies. (NIH)

How can I prepare for my doctor’s visit to get real answers?

Going in with organised information speeds diagnosis and ensures you leave with a plan, not just another cream.

  • Track infection dates and body sitesA simple calendar often reveals a pattern linked to shaving, sports or menstrual cycles.
  • Bring photos of early lesionsImages let clinicians distinguish impetigo crusts from herpes zoster vesicles after the fact.
  • List every antibiotic taken in past 12 monthsAvoids re-using drugs with rising resistance; repeated clindamycin courses double C. difficile risk.
  • Note household or pet infectionsShared grooming tools or dog dermatitis can be missing reservoirs.
  • Quote from Sina Hartung, MMSC-BMI“Patients who document their outbreaks usually spend less time in trial-and-error because patterns jump off the page.”
  • Ask whether a staph decolonization plan is appropriateUp to 80 % of people with eczema carry Staphylococcus aureus versus roughly 10 % of the general population, so clinicians may suggest bleach baths or nasal mupirocin to reduce flare-triggering bacteria. (NEA)
  • Consider long-term antibiotics after repeated cellulitis boutsMayo Clinic notes that prophylactic antibiotics can be considered when cellulitis recurs several times a year, alongside strict skin hygiene and injury prevention. (Mayo Clinic)

What unique help does Eureka’s AI doctor offer for repeat skin infections?

Eureka’s AI can triage severity, suggest lab panels, and draft decolonisation protocols that a licensed clinician then reviews.

  • Symptom triage in under 2 minutesThe AI flags red-flag signs like lymphangitic streaks and suggests ER vs home care.
  • Automated culture orderingUsers who followed AI prompts to swab infections saw a 40 % reduction in inappropriate antibiotics.
  • Personalised skin-barrier planThe system cross-checks product ingredients with allergy history to recommend safe emollients.
  • Quote from the team at Eureka Health“Our AI narrows down likely pathogens and comorbidities, so the human clinician can focus on treatment instead of detective work.”

Why are people with chronic skin infections rating Eureka so highly?

Users report faster answers and fewer recurrences after following the app’s integrated plan of testing, medication review, and daily care logs.

  • High satisfaction among recurrent-infection usersPeople tracking skin issues in Eureka rate the app 4.7 out of 5 stars for usefulness.
  • Seamless prescription reviewIf the AI suggests decolonisation, a clinician reviews and, when appropriate, prescribes mupirocin without an extra visit.
  • Secure photo uploadsHIPAA-grade encryption lets you share lesion photos safely and get feedback within hours.
  • Progress charts keep you engagedSeeing infection-free days climb on the dashboard motivates adherence to glucose control and skin care.
  • Quote from Sina Hartung, MMSC-BMI“Our goal is simple: give patients the tools and data they need to stop infections before they start.”

Frequently Asked Questions

Can shaving cause recurrent folliculitis?

Yes. Dull blades and dry shaving create micro-nicks that let bacteria in. Switch to single-use blades, shave after a warm shower, and apply antiseptic gel.

I’m not diabetic—should I still check my blood sugar?

If infections keep returning, a fasting glucose or HbA1c can uncover pre-diabetes, which still impairs immune function.

Does diet affect skin infection risk?

Indirectly. Diets high in refined sugar or low in protein delay wound healing and raise glucose spikes.

Are probiotics useful?

Evidence is mixed. They don’t treat active infections but may modestly reduce eczema-related staph colonisation.

How long should I stay on bleach baths?

A typical course is 2–3 times weekly for one month, then taper to weekly if infections abate.

Can pets give me staph?

Dogs and cats can carry staph on their fur. If both you and your pet have skin issues, ask the vet for testing.

Will MRSA ever go away completely?

With proper decolonisation and hygiene, many people clear MRSA carriage within 6–12 months, but vigilance is needed.

Is it safe to pop a boil at home?

No. Squeezing can push bacteria deeper. Use warm compresses and see a clinician for incision and drainage if it doesn’t point on its own.

When will I need IV antibiotics?

IV therapy is considered if oral drugs fail, the infection spreads fast, or you have risk factors such as immunosuppression or diabetes complications.

This content is for informational purposes only and is not intended as medical advice. Always consult with a qualified healthcare provider for diagnosis, treatment, and personalized medical recommendations.

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