What is a teratoma with teeth and should I worry about it?

By Sina Hartung, MMSC-BMI, Harvard Medical SchoolReviewed by Eureka Health Medical Group
Published: June 13, 2025Updated: June 13, 2025

Key Takeaways

A teratoma with teeth is a usually benign tumor that grows from germ cells and can form fully developed tissues—most famously teeth, hair, and bone—inside an ovary, testicle, or other mid-line body site. Although 9 in 10 ovarian teratomas are harmless, they can twist, rupture, or turn cancerous, so prompt imaging and surgical removal are often advised.

What exactly is a teratoma with teeth?

A teratoma is a germ-cell tumor containing tissues from all three embryonic layers; about 60 % of mature ovarian teratomas have calcified parts that look like teeth on CT or ultrasound. “Seeing a tooth inside a pelvic mass can be shocking, but it is a textbook sign of a mature cystic teratoma,” explains the team at Eureka Health.

  • Germ cells go off scriptTeratomas start when pluripotent germ cells divide uncontrollably, producing skin, enamel, fat, and nerve tissue in the wrong place.
  • Most common in ovariesUp to 20 % of all ovarian tumors are mature cystic teratomas, often diagnosed between ages 20 and 40.
  • Teeth form from ectodermEnamel-forming cells in the tumor lay down dentin and enamel, creating tooth-like structures visible on X-ray.
  • Usually benign but not innocentOnly 1–2 % undergo malignant transformation, yet 10–15 % cause painful ovarian torsion that needs urgent surgery.
  • Single tooth or eighteen – dental variety inside one tumorCase series describe mature cystic teratomas containing anywhere from one or two teeth to as many as eighteen, occasionally even accompanied by a rudimentary jaw. (PocketDent)
  • Even the brain can host a toothy teratomaA 16-year-old patient developed a giant intracranial mature cystic teratoma that contained two fully formed teeth, proving these tumors can appear well outside the pelvis. (Neurology)

When should a teratoma’s symptoms raise red flags?

Most teratomas stay silent until they reach 5–10 cm, but sudden pain, fever, or rapid growth can mark complications. “Any acute pelvic pain with a known teratoma deserves same-day assessment to rule out torsion,” notes Sina Hartung, MMSC-BMI.

  • Sharp, one-sided pelvic painTwisting of the ovary cuts off blood supply; studies show torsion occurs in 12 % of mature teratomas larger than 6 cm.
  • Fever or rising white countRupture or infection of the cyst leaks sebaceous material and bacteria, leading to peritonitis.
  • New breast tenderness in menA testicular teratoma that secretes hCG can cause gynecomastia; any hormonal change plus a testicular mass needs urgent ultrasound.
  • Rapid increase in size post-menopauseGrowth after age 50 carries a higher (4–6 %) risk of squamous cell carcinoma developing inside the teratoma.
  • Unexplained anemia or jaundiceAuto-immune hemolytic anemia has been documented as a rare paraneoplastic complication of mature cystic teratomas; sudden fatigue, pallor, or jaundice in a patient with an adnexal mass warrants urgent evaluation. (SciELO)
  • Common culprit behind ovarian massesMature cystic teratomas (dermoid cysts) account for roughly 10–20 % of all ovarian growths, so clinicians should keep them high on the differential when pelvic imaging shows a complex cyst. (Discovery)

Could my “tooth tumor” still be something benign?

Yes. Over 90 % of teeth-containing pelvic masses are mature cystic teratomas, but radiologists still rule out look-alikes. The team at Eureka Health points out, “Dermoid cysts and mature teratomas are two names for the same benign entity.”

  • Dermoid cyst equals mature teratomaBoth terms describe a benign cyst lined by skin and containing hair, sebum, or teeth.
  • Epidermoid cysts lack fatPure epidermoid cysts show keratin debris but no calcified teeth and are even less likely to cause trouble.
  • Calcified fibroids mimic teethDegenerating uterine fibroids can calcify in rings, yet they lack the mixed fat-fluid pattern typical of teratomas.
  • Most cases occur in women under 45Population data show that mature ovarian teratomas predominantly affect women younger than 45, aligning with their typical presentation during the reproductive years. (NCBI)
  • Malignant transformation is the rare exceptionReports note that mature cystic teratomas have only a very low rate of malignant change, seen mainly in post-menopausal patients, supporting their overwhelmingly benign nature. (Hindawi)

How can I manage mild symptoms or recovery at home?

After laparoscopic removal, most patients resume routine light activity within a week. “Plan on avoiding heavy lifting for three to four weeks to let the ovary heal,” advises Sina Hartung, MMSC-BMI.

  • Use scheduled pain controlAlternating acetaminophen and NSAIDs provides comparable relief to opioids in 70 % of post-laparoscopy patients.
  • Track your temperature dailyA fever over 100.4 °F after day 3 may signal infection of the surgical site and warrants a call to the surgeon.
  • Add fiber and waterAnesthesia slows gut motility; 25–30 g of dietary fiber plus 2 L water reduces post-op constipation by half.
  • Resume exercise graduallyWalking 10 minutes, three times a day promotes circulation without stressing the healing ovary.

Which tests, imaging, or medicines are used for teratomas with teeth?

Ultrasound is first-line; CT or MRI clarifies anatomy before surgery. The team at Eureka Health says, “The classic appearance is a cyst with fat, a Rokitansky nodule, and bright tooth-like echoes.”

  • Transvaginal ultrasoundDetects 95 % of ovarian teratomas and shows echogenic ‘dermoid plug’ where teeth sit.
  • CT scan for surgical mappingCT quantifies fat, calcification, and relation to bowel; essential when cyst exceeds 10 cm.
  • Tumor markers when cancer suspectedCA-125, CEA, and AFP can support decision-making, though they are normal in most mature teratomas.
  • Prophylactic antibiotics at surgeryOne pre-op dose of cefazolin lowers post-op infection risk from 8 % to under 2 % in dermoid cystectomy.
  • MRI confirms sebaceous fat by T1 hyperintensity that vanishes on fat-saturationRadiologia Brasileira notes that the sebaceous component of mature cystic teratomas mimics retroperitoneal fat on MRI, giving a specific non-invasive signature before surgery. (RB)
  • CT spotting a single erupted tooth guided day-3 excision of an orbital teratomaIn a neonatal case, CT showed a cystic orbital mass containing a tooth, enabling lid-sparing exenteration and confirming benign histology without delay. (PMC)

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This content is for informational purposes only and is not intended as medical advice. Always consult with a qualified healthcare provider for diagnosis, treatment, and personalized medical recommendations.

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