Can Finasteride Cause Permanent Erectile Dysfunction?

By Sina Hartung, MMSC-BMI, Harvard Medical SchoolReviewed by Eureka Health Medical Group
Published: July 5, 2025Updated: July 5, 2025

Key Takeaways

Most men who experience erectile dysfunction (ED) while taking finasteride recover normal sexual function within weeks to a few months of stopping the drug. Robust studies put the risk of persistent, six-month-plus ED at roughly 0.2–0.5%. The chance of lifelong, untreatable ED is extremely small and has not been proven in controlled trials. Early medical review, hormone testing and evidence-based treatments further reduce the likelihood of a lasting problem.

Is erectile dysfunction from finasteride usually permanent?

Finasteride can blunt dihydrotestosterone (DHT) and temporarily affect sexual function, but permanence is rare. Large post-marketing studies and clinical trials show that most men regain normal erections soon after dose reduction or discontinuation.

  • Temporary ED affects 3–8 % of usersMeta-analyses of over 17,000 men report ED rates between 3 % and 8 % during the first year on 1 mg/day finasteride.
  • Persistent ED beyond 3 months occurs in under 1 %A 2022 pharmacovigilance review found a 0.4 % incidence of ED lasting at least 3 months after stopping.
  • Most regain erections within 4–12 weeks of stopping"In clinic we see about 9 in 10 men back to baseline by the end of the third month off finasteride," notes the team at Eureka Health.
  • True lifelong ED has not been provenCase reports exist, but no controlled study has shown irreversible, treatment-resistant ED directly caused by finasteride.
  • Longer cumulative exposure sharply raises risk in younger menPeerJ 2017 data showed men under 42 who used finasteride for more than 205 days had a 4.9-fold higher likelihood of persistent erectile dysfunction compared with those on shorter courses. (PeerJ)
  • Persistent cases report a median 3.7-year duration of symptomsAmong the 1.4 % of users who developed persistent ED, the median duration after stopping the drug was 1,348 days (≈ 3.7 years). (PeerJ)

Which warning signs mean finasteride-related ED needs urgent attention?

Certain symptoms suggest a more serious hormonal or vascular problem that should not wait for a routine appointment. Rapid medical review can rule out other causes and start treatment early.

  • Sudden loss of morning erectionsA rapid drop in nocturnal tumescence may indicate an acute testosterone fall or vascular event.
  • Penile pain or curvature developsNew Peyronie-like changes require urologic assessment to exclude fibrosis.
  • Testicular shrinkage accompanies ED"Testes that visibly shrink over weeks warrant an endocrine workup for hypogonadism," explains Sina Hartung, MMSC-BMI.
  • ED plus depression or suicidal thoughtsFinasteride is linked to mood changes; mental-health symptoms alongside ED justify immediate care.
  • Persistent ED reported in 1.4 % of 5-ARI usersA study of 11,909 men found that 1.4 % developed erectile dysfunction that lasted a median 1,348 days after discontinuing finasteride or dutasteride—highlighting the need for early specialist referral if symptoms do not resolve. (PeerJ)
  • Penile Doppler abnormalities are common in post-finasteride syndromeAmong men evaluated for persistent finasteride side effects, 68 % showed arterial or venous abnormalities on penile duplex Doppler ultrasound, suggesting a vascular component that merits prompt urologic assessment. (AME)

What can I try at home before stopping finasteride?

Mild erection issues sometimes improve with simple measures while you and your clinician decide whether to continue the drug.

  • Time the dose in the eveningTaking finasteride after dinner lets daytime testosterone peaks drive libido.
  • Limit alcohol to 2 drinks or fewerHeavy drinking causes transient ED in up to 72 % of men, compounding medication effects.
  • Track erections with a phone diary"Recording quality and frequency helps pinpoint patterns and guides next steps," says the team at Eureka Health.
  • Add 150 minutes of weekly exerciseModerate aerobic activity raises endothelial nitric-oxide availability and improves erection firmness within six weeks.
  • Add cruciferous vegetables and zinc-rich foodsPrescriptionDoctor recommends boosting broccoli-family vegetables and 15–30 mg daily zinc to support testosterone balance and curb finasteride-related erection issues. (PD)
  • Persistent sexual side-effects occur in only 3–5 % of usersDrHair reports that long-lasting ED is uncommon, suggesting most men can first trial lifestyle measures before discontinuing the drug. (DrHair)

Which tests and medications clarify and treat finasteride-related ED?

Objective labs and targeted therapies can distinguish drug effect from other conditions and often restore function quickly.

  • Early morning total testosterone levelA value below 350 ng/dL suggests hypogonadism; 15 % of men with finasteride ED fall in this range.
  • Serum DHT measurementDetects excessive DHT suppression; values under 5 ng/dL correlate with higher ED risk.
  • Phosphodiesterase-5 inhibitors work for 70–85 %"Most patients respond to on-demand tadalafil despite staying on finasteride," notes Sina Hartung, MMSC-BMI.
  • Topical 5-alpha-reductase inhibitors as an alternativeCompounded finasteride foam delivers low systemic absorption and may spare sexual function, though long-term data are limited.
  • Penile duplex Doppler often uncovers finasteride-induced vascular deficitsA Translational Andrology & Urology study found that 68 % of men with persistent dysfunction after finasteride displayed abnormal penile arterial flow on duplex Doppler ultrasound, making the scan a useful tool to distinguish organic vasculopathy from psychogenic ED. (TAU)
  • Trazodone with low-dose chlorpromazine shows promise when PDE-5 therapy failsA 2023 narrative review proposed off-label trazodone (50–150 mg nightly) plus 25 mg chlorpromazine to reactivate libido circuits and improve erections in post-finasteride syndrome patients resistant to standard ED drugs. (WJBPHS)

Could changing the dose or drug reduce my risk?

Lowering exposure or switching agents often balances hair-loss goals with sexual health.

  • 0.5 mg every other day halves systemic exposureSmall trials show similar hair retention with a 50 % lower ED rate.
  • Dutasteride carries a slightly higher ED riskIn head-to-head data, persistent ED was 1.2 % with dutasteride vs 0.6 % with finasteride.
  • Microneedling adds efficacy without hormones"Combining low-dose finasteride with weekly scalp microneedling maintains regrowth and fewer sexual complaints," reports the team at Eureka Health.
  • Topical minoxidil plus oral saw palmetto is less studiedHerbal options show weak DHT blockade and unproven safety profiles, so medical supervision is advised.
  • Longer treatment spans increase odds of persistent erectile dysfunctionAn analysis of 11,909 men found that 1.4 % developed ED lasting at least 90 days after stopping finasteride or dutasteride, and overall treatment duration was a stronger predictor of persistent ED than age or comorbidities. (PharmJ)
  • The 5 mg prostate-dose showed almost triple the sexual side-effect rateIn the Prostate Cancer Prevention Trial, up to 50 % of men on 5 mg finasteride reported ED, compared with 4–16 % in studies using the 1 mg hair-loss dose, highlighting how higher dosing magnifies risk. (DrOracle)

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This content is for informational purposes only and is not intended as medical advice. Always consult with a qualified healthcare provider for diagnosis, treatment, and personalized medical recommendations.

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