Can an L5 Transitional Vertebra (Sacralization) Be the Real Reason for Your Low-Back Pain?

By Sina Hartung, MMSC-BMI, Harvard Medical SchoolReviewed by Eureka Health Medical Group
Published: June 28, 2025Updated: June 28, 2025

Summary

Yes. When the bottom lumbar vertebra (L5) fuses partly or completely to the sacrum—a variant called sacralization—it can overload the neighboring L4-L5 disk, strain surrounding muscles, and irritate the L5 nerve root. Up to 14 % of people carry this variant, and roughly one-third of them report chronic or recurrent low-back pain that can radiate into the buttock or leg.

How exactly does L5 sacralization lead to low-back pain?

Sacralization changes how forces travel through the spine. The fused segment moves less, so the segment above it moves more and wears out faster. Pain comes from overloaded disks, facet joints, and sometimes pinched nerves.

  • Load shifts upward to L4-L5Finite-element studies show a 22 % increase in shear stress at L4-L5 when L5 is sacralized, predisposing the disk to early degeneration.
  • Facet joints take extra torqueMRI series reveal hypertrophy and inflammation of the L4 facet joints in 43 % of symptomatic patients.
  • Muscle imbalance developsThe deep multifidus muscles above the fusion atrophy by about 15 % cross-sectional area, weakening core stability.
  • Nerve irritation can occurAn aberrant L5 transverse process can compress the L5 nerve root inside the foramen, causing buttock or leg pain.
  • Expert insight on mechanics“Patients often assume the fused bone itself hurts; in reality, it’s the overworked level above it,” explains Sina Hartung, MMSC-BMI.
  • Arthritic pseudo-joints at the transverse process are common pain generatorsThe IJSS review explains that when an enlarged L5 transverse process forms a pseudo-articulation with the sacrum (Castellvi type II/IV), the false joint frequently develops osteoarthritis and osteophytes that can irritate the L5 nerve root and create focal low-back pain. (IJSS)
  • Fluoroscopic injections relieve pain in 86 % of LSTV patientsIn a clinical series of 22 people with lumbosacral transitional vertebrae, 19 (86.4 %) obtained immediate, complete pain relief after steroid–lidocaine was injected into the anomalous articulation, confirming it as the principal pain source. (JStage)

Which pain patterns or red flags mean L5 sacralization needs urgent attention?

Most people experience dull, mechanical pain, but certain symptoms point to complications that should be evaluated quickly.

  • Progressive leg weaknessLoss of ankle dorsiflexion strength or foot drop suggests acute L5 nerve compression and warrants same-week imaging.
  • Bladder or bowel changesNew urinary retention or incontinence together with low-back pain can indicate cauda equina syndrome—call emergency services.
  • Night pain unrelieved by restConstant pain that wakes you up may signal infection or tumor rather than mechanical overload.
  • Severe pain after minor traumaA trivial fall causing intense pain could mean a stress fracture in the pars interarticularis at L4.
  • Doctors underline rapid evaluation“Red-flag symptoms rarely relate to the transitional vertebra itself but must not be ignored,” notes the team at Eureka Health.
  • Lumbosacral transitional vertebrae show a prevalence of 4–21 percent, reaching 30 percent in some imaging seriesBecause most LSTVs are incidental findings, the sudden appearance of neurologic loss or sphincter disturbance should prompt urgent evaluation for superimposed pathology, not the anomaly itself. (CasesJ)
  • Persistent radicular pain may require imaging beyond the usual L5–S1 levelA case report of complete lumbarization revealed calcified disc herniations at both L5–S1 and S1–2 that were initially missed; extended MRI followed by endoscopic discectomy led to rapid neurologic recovery. (Front Surg)

What imaging and tests confirm that the transitional vertebra is the culprit?

Plain X-rays usually spot the abnormal bone, but correlating it with pain takes more. Targeted studies clarify whether the variant is symptomatic.

  • Standing lumbar X-ray classifies fusionRadiologists use the Castellvi grading system (Type I–IV) to describe the degree of sacralization.
  • MRI assesses disk and nerve issuesT2-weighted MRI detects disk dehydration, annular tears, and nerve root impingement above the fusion.
  • CT scan details bony overgrowthWhen surgery is considered, a CT defines the exact anatomy of enlarged transverse processes or pseudo-joints.
  • Diagnostic anesthetic injectionsPain relief after facet or pseudo-arthrosis block adds evidence that the level is pain-generating.
  • Expert quote on precision testing“Combining MRI with a diagnostic injection raises the accuracy of identifying the painful segment to over 80 %,” states Sina Hartung, MMSC-BMI.
  • Injection into the pseudo-articulation relieved pain in 86 % of casesAmong 22 patients with LSTV-related low back pain, 19 experienced immediate, complete relief after fluoroscopy-guided steroid–lidocaine injection, confirming the transitional segment as the pain source. (Jstage)
  • Bone scan uptake plus anesthetic block strengthens diagnostic confidenceElevated radionuclide uptake at the enlarged transverse process, coupled with a positive local anesthetic injection, is highlighted as a reliable method to identify a symptomatic transitional vertebra. (IJSS)

Which daily habits actually reduce pain from a sacralized L5?

Targeted self-care often stabilizes the overloaded segment and limits flare-ups.

  • Core-centric exercise beats restA 12-week program of bird-dog and side-plank exercises cut pain scores by 46 % in one clinical pilot.
  • Hip mobility protects the spineStretching the hip flexors and gluteals for 60 s per side, twice daily, offloads lumbar extension forces.
  • Ergonomic tweaks matterUsing a lumbar-support cushion reduces intradiskal pressure at L4-L5 by up to 25 % while sitting.
  • Activity pacing prevents overuseBreak tasks into 20-minute blocks to avoid sudden spikes in facet joint load.
  • Team perspective on adherence“Consistency, not intensity, is what keeps these patients out of the doctor’s office,” observes the team at Eureka Health.
  • Heat or ice sessions calm flare-upsConservative care guidelines for a sacralized L5 include applying heat or cold packs to reduce local muscle spasm and irritation when pain suddenly increases. (DrOracle)
  • Condition affects up to one-third of adultsEpidemiological reviews place the incidence of lumbosacral transitional vertebrae, including L5 sacralization, between 4 % and 36 % of the population, underscoring the value of preventive daily habits. (Healthline)

Which labs and treatments might your clinician order for L5 sacralization pain?

There is no blood test for the variant, but certain labs and medications help rule out mimics and control symptoms.

  • Inflammatory markers when pain is atypicalESR and CRP help exclude infection or inflammatory spondyloarthritis if pain is constant or accompanied by fevers.
  • NSAIDs remain first-lineShort courses can cut prostaglandin-mediated inflammation in hyper-mobile facet joints; discuss GI and kidney risks with your prescriber.
  • Muscle relaxants for acute spasmAgents like cyclobenzaprine may provide temporary relief but are best limited to 1–2 weeks to avoid sedation.
  • Image-guided steroid injectionsCT-guided L4 facet or pseudo-arthrosis injections yield 60–70 % short-term pain reduction in observational studies.
  • Expert comment on cautious use“Medication masks pain; it doesn’t fix mechanics. Combine it with rehab from day one,” advises Sina Hartung, MMSC-BMI.
  • Sacralization lowers steroid injection successIn a 2022 prospective study, only 44.8 % of Bertolotti patients achieved ≥50 % pain reduction three months after a transforaminal epidural steroid injection compared with 65.6 % of those without the variant. (PubMed)
  • Endoscopic resection offers relief when conservative care failsA reported case showed a patient who exhausted physical therapy, SI-joint injections and spinal cord stimulation experienced sustained pain relief following minimally invasive excision of the pseudo-articulation. (PMC)

How can Eureka’s AI doctor help decide if your pain is from a transitional vertebra?

Eureka’s AI platform uses your symptom timeline, functional limits, and any existing imaging to create a probability score for mechanical versus inflammatory causes.

  • Automated red-flag triageIf you enter leg weakness or bladder issues, the AI flags emergent care and explains why within 10 seconds.
  • Personalized imaging guidanceBased on age, pain pattern, and prior tests, the AI may suggest adding an MRI with specific lumbar protocols.
  • Draft questions for your visitUsers receive a checklist—like asking about Castellvi grade or considering a diagnostic block—improving consult efficiency.
  • Expert-review guaranteeAll imaging or medication suggestions are double-checked by the clinical team at Eureka Health before release.
  • Quote on decision support“We designed the system to close the gap between vague back-pain complaints and targeted, evidence-based care,” says the team at Eureka Health.

What does day-to-day management look like when you use Eureka for L5 sacralization?

Beyond the initial assessment, the app helps users stay consistent with rehab and tracks which interventions actually help.

  • Symptom tracking with visual trendsPain scores and activity levels plot on a dashboard, letting you see how core workouts correlate with pain drops.
  • Adaptive exercise plansIf pain spikes after a new exercise, the AI swaps in a lower-shear alternative within 24 hours.
  • Medication reminder and taper toolUsers receive alerts to re-evaluate NSAID use every 7 days, supporting safe, short-term courses.
  • 4.8-star satisfaction from spine-pain usersIn post-session surveys, people managing transitional vertebra pain rate Eureka 4.8/5 for ease of use and feeling heard.
  • Sina Hartung on user empowerment“Seeing objective data—like fewer pain spikes after three weeks of hip stretches—keeps patients motivated,” notes Sina Hartung, MMSC-BMI.

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Frequently Asked Questions

Can sacralization of L5 heal or reverse on its own?

The bony fusion is permanent, but pain often improves by offloading the segment with targeted exercise and posture changes.

Is surgery common for a sacralized L5?

Only about 5 % of symptomatic patients need surgery such as resection of an enlarged transverse process or fusion of the adjacent level.

Why does my MRI say “Bertolotti syndrome”?

Bertolotti syndrome is simply the clinical term for pain linked to an L5 transitional vertebra; it is not a separate disease.

Will a standing desk help?

Yes—alternating sitting and standing every 30 minutes reduces lumbar disk pressure and may lessen flare-ups.

Do shoe inserts matter for this condition?

If you have leg-length discrepancy from pelvic tilt, custom orthotics can level the hips and reduce asymmetric loading.

Is running safe with L5 sacralization?

Light jogging is fine if core strength is good and pain stays below 3/10; add rest days and avoid hard surfaces during flare-ups.

How long should I try conservative care before considering injections?

Most spine specialists recommend at least 6–12 weeks of structured rehab before invasive procedures unless red-flag symptoms exist.

Can pregnancy worsen pain from a transitional vertebra?

Hormonal ligament laxity and weight gain can increase strain on L4-L5; wearing a maternity support belt often helps.

This content is for informational purposes only and is not intended as medical advice. Always consult with a qualified healthcare provider for diagnosis, treatment, and personalized medical recommendations.